Monthly Archives: July 2013

From The Desk Of Dr. Hildy – DR. HILDY’S GARDEN COLLECTION

Dr. Hildy®’s Garden

Collection

A Time for Tea,

Your Favorite Recipe

or Bath

ESSENCE

 
Dr. Hildegarde Staninger®,RIET-1, Industrial Toxicologisthas been searching the various lands and seas to bring forth to our clients and patients the most purist and highest bio-active botanicals, that could be found in the world. The Dr. Hildy®’s Garden Collection is a collection of Authentic Natural Pure Spice Essencethat allows you to add taste to a hot cup of tea or beverage and use it in your favorite cooking recipes.  You may even squirt it in your bath or foot bath water to give you the added botanical health benefits to your skin and body. The precious anti-oxidants, rich flavors and natural phytochemicals, all remain intact and ready for instant release as you simply pump into water, juices or any liquid base. There is absolutely no waste and each bottle does 100 servings of instant flavor, no heating required, disperses evenly, long shelf life for a Natural and Healthy product.

The Introductory Offer to the Dr. Hildy®’s Introductory Garden Collection was hand-picked by Dr. Staninger to include her favorite spices, which would help nurture your bodies healing process, as it became more naturally radiant.

She recommends that you may use

1 squirt in your favorite beverage or foot bath water

and 2 squirts for your bath tub water. 

These spices may be used individually in the bath or with:   

Baci Mi® Bebe Bath Time

 Chac Mool®  Yellow/Clear/Jade/Purple

or Willard’s Water® for added benefits.***

Pure Spice Essence was created by Primal Essence, Inc, Oxnard, CA. It is made of high grade, non-irradiated spices and uses ultra high technology called Supercritical Fluid Extraction. The yield is a pure, chemical-free, alcohol-free, Pure Spice Essence, which is many times more potent than any dried herb or spice product.

The ‘Pure Spice Essences’ Health Benefits and Healing Properties are as follows for each of the DR. Hildy®’s selected spice/herbs ~

 Lemongrass, Basil and Peppermint

for this special

Introductory Garden Collection bundle.

 Lemon Grass~Lemongrass~ has been recommended for cough, cold & sore throat; anxiety, high cholesterol, Type 2 diabetes; colitis, digestion; rough, dry, scaly skin; acne; constipation; kidney detoxification; insomnia; relaxation and deep sleep. Lemongrass contains citral which has strong anti-microbial and anti-fungal properties.  Its leaves and stems are high in folic acid and essential vitamins such as pantothenic acid (vitamin B5), pyridoxine (vitamin B6) and thiamin (vitamin B1). It also contains many anti-oxidant minerals and vitamins such as vitamin C, vitamin A, potassium, zinc, calcium, iron, manganese, copper and magnesium.  Lemongrass is highly effective in flushing toxins and wastes out of the body; improving the function of many different organs including the liver, spleen and kidneys.

PEPPERMINT~Peppermint ~ has been recommended for acne, headaches, migraines, head lice, irritable bowel syndrome, menstrual cramps, pain relief, sinusitis, colds, stress and anxiety. Studies have shown that Peppermint can help with a number of health conditions. It is known to have analgesic, anesthetic, decongestant, astringent, antiseptic, antibacterial, antimicrobial, antispasmodic, and carminative properties. Therefore, it has been found beneficial in the treatment of many conditions including colds, flu, sinusitis, dry cough, fever with chills, nausea, digestive problems, mood swings and emotional imbalance.

~BBASILasil ~ Basil is known as the “Mediterranean”cultivar typically called sweet basil. Its leaves contain many notable plant derived chemical compounds that are known to have disease preventing and health promoting properties, anti-oxidant protection against radiation-induced lipid peroxidation from its polyphenolic flavonoids like orientin and vicenin, while eugenol, citronellol, linalottl, citral, limonene and terpineol are known to have anti-inflammatory and anti-bacterial properties.   It is low in calories and contains no cholesterol, but is very rich source of many essential nutrients, minerals and vitamins that are required for optimum health. 

Basil herb contains exceptionally high levels of beta-carotene, vitamin A, cryptoxanthin, leutein and zeaxanthin. These compounds help act as protective scavengers against oxygen-derived free radicals and reactive oxygen species (ROS) that play a role in aging and various disease processes.  Zea-zanthin, a yellow flavonoid carotenoid compound, is selectively absorbed into the retinal macula lutea where it is found to filter harmful UV rays from reaching the retina. Studies suggest that common herbs, fruits, and vegetables that are rich in zea-xanthin anti-oxidant help to protect fro age-related macular disease (AMRD), especially in the elderly. Vitamin K in basil is essential for many coagulant factors in the blood and plays a vital role in the bone strengthening function by helping mineralization process in the bones.

 

The Suggested Retail Price for each individual squirt bottle of

Pure Essence Spice of

Lemongrass, Peppermint or Basil:

$19.95, each.

ESSENCE

Dr. Hildy®’s Introductory Garden Collection

of ALL 3 Pure Essence Spices:

only $49.95, while supplies last.

Dr. Hildy®’s Introductory Garden Collection is a significant cost savings for YOU, as you get ready to make those special Heirloom Family recipes and just treat yourself to something special.

Just because you are YOU!

ihs-clients@sbcglobal.net  ~   www.onecellonelightradio.wordpress.com

IHS_PRODUCT_GUIDE_DR_HILDY_07-18-2013.pdf

TO ORDER DR. HILDY’s FiNE PRODUCTs:

Integrative Health Systems, LLC
415 ¾ N. Larchmont Blvd.
Los Angeles, CA 90004

Phone: 323-466-2599
Fax: 323-466-2774

eMail: ihs-clients@sbcglobal.net

~~~~~~~~ All information contained herein is for educational purposes. The information has not been evaluated by the Food and Drug Administration, except where FDA documents are provided. The information is not intended to replace medical care, diagnose, treat, prevent, mitigate or cure disease. We believe in the individual’s informed right to choose their own health care methods. As always, consult with a health professional before attempting any self-health program. Your physician can assist you in making  decisions. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

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From The Desk of Dr. Hildy – Heirloom Special with ‘A Pinch Of Love…” by Mariana Zaharoff

specialbundle

MARIANA

Our Heirloom Special consists of

“A Pinch of Love in Everything You Cook”

by Mariana Zaharoff,

International Fashion Designer

It takes four hours to Hand PAINT the cook book by Mariana Zaharoff. 

The book is not just a book, it is an Heirloom, that may be passed down through generations or to your favorite person who loves to cook within your family or circle of friends. The Heirloom Bundle is an ideal Birthday, Anniversary, Holiday or just something to give to that special someone in your life – YOU.

The Heirloom Special Bundle contains the following:

                                                            Suggested Retail Price

1-copy of the Cook book by Mariana Zharoff   $  50.00

1- Peppermint liquid spice, 1 oz. Primal Essence, Inc.                                                                                                                         $  19.95

1-Baci Mi® Lemon Drop Gel                                  $  29.95  

                                                                  Total  $  99.90

             ● IHS Special Bundle Price 5% off – $94.50 

                    

The Heirloom Special is Exclusively Offered ONLY at:

Integrative Health Systems®, LLC ~

415 ¾  N. Larchmont Blvd, Los Angeles, CA 90004

(323) 466-2599

ihs-clients@sbcglobal.net

~~!~!~!~!~!~!~!~!~!~!~~

COME LISTEN !! OneCellOneLightRadio

July 17, 2013 – 1:00-3:00PM Pacific
Dr. Hildy is joined by Mariana Zaharoff
and her Grandson, Warren Bisch

www.onecellonelightradio.wordpress.com

FROM THE DESK OF DR. HILDY® – Acetaminophen and Paracetamol – Glutathione Reaction

COME visit the website and listen to the July 10, 2013
OneCellOneLightRadio show with Dr. Hildy® – 1-3:00PM Pacific
 and archived thereafter – 
TODAY’S SUBJECT:
*GLUTATHIONE and It’s Role In The Biotransformation of TOXICANTS*
.
Life and Health Enhancing information!
.
FROM THE DESK OF DR. HILDY®
by Dr. Hildegarde Staninger®, RIET-1
© July 1, 2013

ACETAMINOPHEN & PARACETAMOL and THEIR REACTION TO GLUTATHIONE

Recently, I co-authored a paper that is being published by the National Registry of Environmental ProfessionalsTM, Glenview, IL for their Professional Journal.   The paper is entitled:  “Glutathione and Its Role in the Biotransformation of Toxicants.”  The paper is a must read paper for anyone who has been exposed to industrial solvents, venoms, hazardous materials, medications and other toxic chemical substances.    The paper did not address a primary study that was conducted by J.R. Mitchell (1973) which specifically addressed the protective role of glutathione upon induced hepatic necrosis from exposure to the compound acetaminophen (paracetamol, the international nonproprietary name) an active ingredient in the medication Tylenol®.1, 2, 3a,b

The paper discusses the role of Xenobiotics and their metabolites.   A xenobiotic is a chemical which is found in an organism but which is not normally produced or expected to be present in it. It can also cover substances which are present in much higher concentrations than are usual. Specifically, drugs such as antibiotics are xenobiotics in humans because the human body does not produce them itself, nor are they part of a normal diet.

Natural compounds can also become xenobiotics if they are taken up by another organism, such as the uptake of natural human hormones by fish found downstream of sewage treatment plant outfalls, or the chemical defenses produced by some organisms as protection against predators.

However, the term xenobiotics is very often used in the context of pollutants such as dioxins and polychlorinated biphenyls and their effect on the biota, because xenobiotics are understood as substances foreign to an entire biological system, i.e. artificial substances, which did not exist in nature before their synthesis by humans. The term xenobiotic is derived from the Greek words ξένος (xenos) = foreigner, stranger and βίος (bios, vios) = life, plus the Greek suffix for adjectives -τικός, -ή, -ό (tic).4 a, b

Free reactive electrophilic intermediates of xenobiotics can produce damage to important cellular consitituents.  Reduced gluathione and the glutathione S-transferase protect cells from this damage by capturing reactive electrophiles before they react at nuceleophilic sites critical to cell viability.5

The metabolism of acetaminophen, an analgesic that at high doses can produced hepatic necrosis, serves as an example of this protective system.  A large body of work has shown that one of the principal ways in which acetaminophen produces its hepatotoxicity is via the reactive intermediate, N-acetyl-p-benzoquinone imines shown in Figure 1.  This intermediate is apparently a soft electrophile that reacts readily with the strong, soft nucleophile glutathione.  As long as the amount of glutathione present at the site of activation of acetaminophen is sufficient to bind the reactive intermediate, no toxicity ensues.  However, as was demonstrated in a classic study by Mitchell et al.6, when glutathone is depleted by pretreatment with diethylmaleate, the benzoquinone imine covalently binds to tissue proteins resulting in tissue necrosis.  Mitchell et. al.6 were among the first to propose that glutathione plays a fundamental role in protecting tissue against electrophilic attack by xenobiotics.7

Since these early studies demonstrating the protective role of glutathione, many compounds have been shown to form conjugates with glutathione.  The protective interaction of glutathione and its primary sulfur dependent enzyme, glutathione-S-transferase play a major role in hormonal regulation of substrate supply to the small intestine.  Insulin, glycogen, and catecholamines are the most important hormones that regulate the supply of glucose, fatty acids, and ketone bodies in most tissue.  Early studies by W.C. Hulsmann concluded that the direct effect of these hormones on small intestinal epithelium may be modest or negligible, while interaction of streptozotocin-diabetic rat, showed the vascularly profused small intestine diminished glucose utilization.  This, however, is probably due to the glucose sparing action of fatty acids and ketone bodies upon intestinal energy metabolism, because of the observation that in diabetes the rate of lactate formation is not decreased.8 a,b, 9

It is very important to note that glutathione plays a major role in detoxification, walling up the toxicants and adding a chain of beneficial mechanisms need to protect one from the chronic effects of hormones, such as thyroid hormones and glucocorticoids that are further stimulated or inhibited upon exposure to thiols/mercaptans.10

REFERENCES

1)  Staninger, Hildegarde and Daniel F. Farrier.  Glutathione and Its Role in the Biotransformation of Toxicants.  Journal of the National Registry of Environmental Professionals.  Glenview, IL  © June 28, 2013.

2)  Sacarello, Hildegarde and Scott J. Evans.  Genetic Cancer Risk Assessment of Electrophilic Hydrocarbon Mixtures in Subsurface Water Supplies. US EPA Agency:  Research and Development.  Symposium on short-Term Genetic Bioassays in the Evaluation of Complex Environmental Mixtures.  Hotel Europa.  Chapel Hill, North Carolina.  March 27-29, 1984

3) (a) Hayes, A. Wallace.  Principles and Methods of Toxicology, Second Edition. Chapter 2:  Metabolism: A Determinant of Toxicity by J. Donald deBethizy and Johnnie R. Hayes.  Raven Press, Ltd., New York, New York © 1989 pgs 29-69.

(b) http://en.wikipedia.org/wiki/Tylenol

4)  (a) http://en.wikipedia.org/wiki/Xenobiotic.com

(b) Mentuccia, Roberto and Hildegarde Staninger.  Increase or Boost Your Metabolism.   Integrative Health Systems®, LLC.  Los Angeles, CA  © June 7, 2011

5)  Mitchell, J.R. Acetaminophen-induced hepatic necrosis.  IV. Protective role of glutathione.  J. Pharmacol. Exp. Ther., 187: 211-217, © 1973

6)  Mohandas, J., Duggin, G.G., Horvath, J.S. and D.J. Tiller.  Metabolic oxidation of acetaminophen (paracetamol) mediated by cytochorme P-450 mixed-function oxidase and prostaglandin endoperoxide synthetase in rabbit kidney.  Toxicol. Appl. Pharmacol.  61:252-259.

7)  Morgan, E.T., and M.J. Coon.  Effects of cytochrome b5 on cytochrome P-450 catalyzed reactions:  Studies withmanganese substituted cytochrome b5. Drug Metab. Dispos., 12: 358-364.

8) (a) Hulsmann, W.C.  Abnormal stress reactions after feeding diets rich in (very) long chain fatty acids:  high levels of corticosterone and testosterone.  Mol. Cell. Endocrinol., 12: 1-8 (C) 1978

(b)  Hulsmann, W.C.  Energy metabolism in different preparations of rat small intestinal epithelium.  In:  Intestinal Permeation.  Proceedings of the Fourth Workshop Conference Hoescht, edited by M. Kramer and F. Lauterbach, pp. 229-239.  Excerpta Medica Intern. Congress Series 391, Excerpta Medica, Amsterdam.

9.  Lamers, J.M.J. and W.C. Hulsmann. The effects of fructose on the stores of energy-rich phosphate in rat jejunum in vivo.   Biochim.  Biophys. Acta.  313: 1-8. © 1973

10.  Schille, Carol M.  Intestinal Toxicology.  Target Organ Toxicology Series.  Editor-in-Chief Robert L. Dixon.  Raven Press, Ltd.  New York, New York © 1984

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