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Believe Me: My Battle with the Invisible Disability of Lyme Disease by Yolanda Hadid

YOLANDA HADID’s NEW BOOK

Believe Me: My Battle with the Invisible
Disability of Lyme Disease
by Yolanda Hadid
St. Martin’s Press © 2017

To ALL Our Fans at “One Cell One Light®” Radio Show:

I want to guide you to read the book by Ms. Yolanda Hadid, entitled Believe Me: My Battle with the Invisible Disability of Lyme Disease, which just hit the book shelves on September 12, 2017. (www.amazon.com & www.barnesandnoble.com)

The book brings out the various healthcare providers she saw throughout her journey to recovery in her battle against Lyme Disease. She even discusses on certain pages going to see her toxicologist, Dr. Hildegarde Staninger®, RIET-1, where she learned about essential oils, rose and orange water.

Over the years I have recommended to Lyme and other patients/clients the essential oil soft gels such as Slim & Sassy; Triease; Digest Zen and On Guard, manufactured by doTerra® (www.doterra.con/drhildy).  And  don’t  forget  my recipes for Orange and Rose water we use in our Dr. Hildy®’s Whole Body Detoxification and Environmental Health Educational Programs (.pdf).   They are quite refreshing.

Currently, I have reviewed the ingredients of a coffee that is designed to stimulate internal thermogenesis, which interact with your mitochondria and stimulates heat production, so it will allow the mitochondria to function properly as it burns fat (to reduce weight) and increase circulation. It is called Revital U Brew. It is known to reset your cells to remember who they were originally as created. This is so important to so many environmental stress factor exposures that may lead to increasing the potential risk of initiating an illness or disease over time. www.revitalu.com/drhildy

Revital U Brew was introduced to my listeners on the One Cell One Light Radio Show during our Labor Day Weekend Show, September 4, 2017. “Flowers are for Beauty, Fruit and Nuts are for Health,”  (https://onecellonelightradio.wordpress.com/2017/09/04/dr-hildy-presents-flowers/ ) because a coffee bean is a hard nut to crack and that is why we grind it.

Coming soon, before the year 2017 is over, we will have a show about my new book Cricket the K-Town Kitty: A Tale of Who I Am . Our special guest on the show will  be the leading authoritarian on Ancient Cat Ancestry, as reported in the National Geographic magazine, Dr. Leslie Lyons, Professor, University of Missouri.

Purchase these new books so you will know the answers to the special prize questions, when you try to win a very SPECIAL Dr. HILDY PRIZE that includes the new Baci Mi®  Gel “Ciao Ciao Meow” in honor Cricket the K-Town Kitty.  (An announcement for ordering will be published here when the book is released – soon! –  by the publisher – Cricket the K-Town Kitty: A Tale of Who I Am )

Ciao Ciao Meow from
Dr. Hildy
®  and Cricket the K-Town Kitty
© September 18, 2017

Integrative Health Systems®, LLC
415 ¾ N. Larchmont Blvd.
Los Angeles, CA 90004
Phone: 323-466-2599
Fax: 323-466-2774

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FROM THE DESK OF DR. HILDY® – Acetaminophen and Paracetamol – Glutathione Reaction

COME visit the website and listen to the July 10, 2013
OneCellOneLightRadio show with Dr. Hildy® – 1-3:00PM Pacific
 and archived thereafter – 
TODAY’S SUBJECT:
*GLUTATHIONE and It’s Role In The Biotransformation of TOXICANTS*
.
Life and Health Enhancing information!
.
FROM THE DESK OF DR. HILDY®
by Dr. Hildegarde Staninger®, RIET-1
© July 1, 2013

ACETAMINOPHEN & PARACETAMOL and THEIR REACTION TO GLUTATHIONE

Recently, I co-authored a paper that is being published by the National Registry of Environmental ProfessionalsTM, Glenview, IL for their Professional Journal.   The paper is entitled:  “Glutathione and Its Role in the Biotransformation of Toxicants.”  The paper is a must read paper for anyone who has been exposed to industrial solvents, venoms, hazardous materials, medications and other toxic chemical substances.    The paper did not address a primary study that was conducted by J.R. Mitchell (1973) which specifically addressed the protective role of glutathione upon induced hepatic necrosis from exposure to the compound acetaminophen (paracetamol, the international nonproprietary name) an active ingredient in the medication Tylenol®.1, 2, 3a,b

The paper discusses the role of Xenobiotics and their metabolites.   A xenobiotic is a chemical which is found in an organism but which is not normally produced or expected to be present in it. It can also cover substances which are present in much higher concentrations than are usual. Specifically, drugs such as antibiotics are xenobiotics in humans because the human body does not produce them itself, nor are they part of a normal diet.

Natural compounds can also become xenobiotics if they are taken up by another organism, such as the uptake of natural human hormones by fish found downstream of sewage treatment plant outfalls, or the chemical defenses produced by some organisms as protection against predators.

However, the term xenobiotics is very often used in the context of pollutants such as dioxins and polychlorinated biphenyls and their effect on the biota, because xenobiotics are understood as substances foreign to an entire biological system, i.e. artificial substances, which did not exist in nature before their synthesis by humans. The term xenobiotic is derived from the Greek words ξένος (xenos) = foreigner, stranger and βίος (bios, vios) = life, plus the Greek suffix for adjectives -τικός, -ή, -ό (tic).4 a, b

Free reactive electrophilic intermediates of xenobiotics can produce damage to important cellular consitituents.  Reduced gluathione and the glutathione S-transferase protect cells from this damage by capturing reactive electrophiles before they react at nuceleophilic sites critical to cell viability.5

The metabolism of acetaminophen, an analgesic that at high doses can produced hepatic necrosis, serves as an example of this protective system.  A large body of work has shown that one of the principal ways in which acetaminophen produces its hepatotoxicity is via the reactive intermediate, N-acetyl-p-benzoquinone imines shown in Figure 1.  This intermediate is apparently a soft electrophile that reacts readily with the strong, soft nucleophile glutathione.  As long as the amount of glutathione present at the site of activation of acetaminophen is sufficient to bind the reactive intermediate, no toxicity ensues.  However, as was demonstrated in a classic study by Mitchell et al.6, when glutathone is depleted by pretreatment with diethylmaleate, the benzoquinone imine covalently binds to tissue proteins resulting in tissue necrosis.  Mitchell et. al.6 were among the first to propose that glutathione plays a fundamental role in protecting tissue against electrophilic attack by xenobiotics.7

Since these early studies demonstrating the protective role of glutathione, many compounds have been shown to form conjugates with glutathione.  The protective interaction of glutathione and its primary sulfur dependent enzyme, glutathione-S-transferase play a major role in hormonal regulation of substrate supply to the small intestine.  Insulin, glycogen, and catecholamines are the most important hormones that regulate the supply of glucose, fatty acids, and ketone bodies in most tissue.  Early studies by W.C. Hulsmann concluded that the direct effect of these hormones on small intestinal epithelium may be modest or negligible, while interaction of streptozotocin-diabetic rat, showed the vascularly profused small intestine diminished glucose utilization.  This, however, is probably due to the glucose sparing action of fatty acids and ketone bodies upon intestinal energy metabolism, because of the observation that in diabetes the rate of lactate formation is not decreased.8 a,b, 9

It is very important to note that glutathione plays a major role in detoxification, walling up the toxicants and adding a chain of beneficial mechanisms need to protect one from the chronic effects of hormones, such as thyroid hormones and glucocorticoids that are further stimulated or inhibited upon exposure to thiols/mercaptans.10

REFERENCES

1)  Staninger, Hildegarde and Daniel F. Farrier.  Glutathione and Its Role in the Biotransformation of Toxicants.  Journal of the National Registry of Environmental Professionals.  Glenview, IL  © June 28, 2013.

2)  Sacarello, Hildegarde and Scott J. Evans.  Genetic Cancer Risk Assessment of Electrophilic Hydrocarbon Mixtures in Subsurface Water Supplies. US EPA Agency:  Research and Development.  Symposium on short-Term Genetic Bioassays in the Evaluation of Complex Environmental Mixtures.  Hotel Europa.  Chapel Hill, North Carolina.  March 27-29, 1984

3) (a) Hayes, A. Wallace.  Principles and Methods of Toxicology, Second Edition. Chapter 2:  Metabolism: A Determinant of Toxicity by J. Donald deBethizy and Johnnie R. Hayes.  Raven Press, Ltd., New York, New York © 1989 pgs 29-69.

(b) http://en.wikipedia.org/wiki/Tylenol

4)  (a) http://en.wikipedia.org/wiki/Xenobiotic.com

(b) Mentuccia, Roberto and Hildegarde Staninger.  Increase or Boost Your Metabolism.   Integrative Health Systems®, LLC.  Los Angeles, CA  © June 7, 2011

5)  Mitchell, J.R. Acetaminophen-induced hepatic necrosis.  IV. Protective role of glutathione.  J. Pharmacol. Exp. Ther., 187: 211-217, © 1973

6)  Mohandas, J., Duggin, G.G., Horvath, J.S. and D.J. Tiller.  Metabolic oxidation of acetaminophen (paracetamol) mediated by cytochorme P-450 mixed-function oxidase and prostaglandin endoperoxide synthetase in rabbit kidney.  Toxicol. Appl. Pharmacol.  61:252-259.

7)  Morgan, E.T., and M.J. Coon.  Effects of cytochrome b5 on cytochrome P-450 catalyzed reactions:  Studies withmanganese substituted cytochrome b5. Drug Metab. Dispos., 12: 358-364.

8) (a) Hulsmann, W.C.  Abnormal stress reactions after feeding diets rich in (very) long chain fatty acids:  high levels of corticosterone and testosterone.  Mol. Cell. Endocrinol., 12: 1-8 (C) 1978

(b)  Hulsmann, W.C.  Energy metabolism in different preparations of rat small intestinal epithelium.  In:  Intestinal Permeation.  Proceedings of the Fourth Workshop Conference Hoescht, edited by M. Kramer and F. Lauterbach, pp. 229-239.  Excerpta Medica Intern. Congress Series 391, Excerpta Medica, Amsterdam.

9.  Lamers, J.M.J. and W.C. Hulsmann. The effects of fructose on the stores of energy-rich phosphate in rat jejunum in vivo.   Biochim.  Biophys. Acta.  313: 1-8. © 1973

10.  Schille, Carol M.  Intestinal Toxicology.  Target Organ Toxicology Series.  Editor-in-Chief Robert L. Dixon.  Raven Press, Ltd.  New York, New York © 1984

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FROM THE DESK OF DR. HILDY® https://onecellonelight.wordpress.com

Integrative Health Systems®, LLC – Dr. Staninger’s® Website www.staningerreport.com

RESEARCH: Dr. Hildegarde Staninger®, RIET-1 http://www.1cellonelight.com/index-4.html

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6/27/12 – FROM THE DESK OF DR. HILDY™ – Vitamin B-12

FROM THE DESK OF DR. HILDY™                  VITAMIN B12

by Dr. Hildegarde Staninger, RIET-1         Series 1:  Vitamins & Minerals

© May 26, 2012

Vitamin B-12 Sources

(This vitamin is found mainly in liver, kidney, muscle meats, oysters, milk, eggs, cheese and salt-water fish.  Of the vegetable foods, yeast, wheat germ and soybeans have cobalimin content, but  only small traces of it.)

ONE CELL ONE LIGHT RADIO
with Dr. Hildegarde Staninger

LISTEN TO HOUR 2 – Dr. Hildy and Shoshanna discuss B-VITAMINS and specifically Vitamin B-6 and then Vitamin B-12

~~~ Archived here for your listening convenience~~~
http://www.blogtalkradio.com/onecellonelightradio/2012/06/27/62712-drhildy-sandra-lemiree-girls-entrepreneurial-women

This vitamin is essential for the blood-forming organs of the bone marrow if they are to function properly.  Also, the nervous system depends upon this vitamin for nutrition.  One of the ingredients of this vitamin is cobalt, and it appears from the study of scientific materials that Vitamin B12 is now being referred to as cobalamin, because of the importance of cobalt in the diet.  Likewise, zinc is associated with this vitamin, the studies indicating that the vitamin cannot be synthesized without the help of zinc.  Vitamin B12 is also needed to help form hemoglobin scale.  Thus this vitamin is important for the prevention of anemia.  It also combines with folic acid to help produce the vital red blood cells.  Actually, it has been stated that less than one millionth of a gram of cobalamin is needed daily to meet the human body requirements.

The lack of cobalamin may cause pernicious anemia, due to the inability of the bone marrow to form blood when this vitamin is absent.  A symptom of lack of cobalamin is a shuffling gait.  Another indication is a loss of sense of position of the feet.  In severe cases, where there has been a degeneration of the spinal cord, there may be nerve and brain damage and even complete paralysis.

Another result of this deficiency is general malnutrition, marked by an insufficient production of sex hormones with the resultant lack of development or shriveling of Read the rest of this entry

Increase or Boost Your Metabolism

Roberto Mentuccia & Dr. Hildegarde Staninger™, RIET-1
Integrative Health Systems™, LLC © June 7, 2011

What is the Definition of Metabolism?
Metabolism is a term used to describe the process of breaking down a complex molecule to produce energy. Think of your body’s metabolism as a furnace, (it will help for explanation purposes). Often metabolism is associated with the term BMR which stands for Basal Metabolic Rate (also called Resting Metabolic Rate or RMR). BMR is a term used to describe the amount of energy your body uses at rest to survive. Increasing your Basal Metabolic Rate is a highly desirable effect which most of society is trying to achieve. You can purchase a BMR calculator or search the internet for an automatic calculator to assist you.

Read the rest of this entry